The DNA-binding domain occupies residues 1–59. It contains two a-helices separated by a turn. This is a common DNA-binding motif known as the HTH (helix-turn-helix); the two a-helices fit into the major groove of DNA

TLS Online TPP Program

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#Unit 10. Ecological Principles

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#Id: 1746

#Unit 4. Cell Communication and Cell Signaling

IFN-  has been shown to induce expression of the class II transcriptional activator (CIITA).

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#Unit 4. Cell Communication and Cell Signaling

IL-4 increases expression of class II molecules in resting B cells, turning them into more efficient APCs.

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#Unit 3. Fundamental Processes

For DNA replication, a special RNA polymerase called a primase synthesizes an RNA chain that provides the priming end.

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#Unit 3. Fundamental Processes

The SL RNA provides an exon that is connected to the first exon of an mRNA by trans-splicing. The reaction involves the same interactions as nuclear cis splicing but generates a Y-shaped RNA instead of a lariat.