The α-amanitin binding site is beneath a “bridge helix” extending across the cleft between the two largest pol II subunits, Rpb1 and Rpb2

a DNA template, whereas in eukaryotes, transcription takes place on a chromatin template.

TLS Online TPP Program

#Id: 752

#Unit 3. Fundamental Processes

DNA polymerase binds two divalent metal ions (typically Mg2+ orZn2+) that alter the chemical environment around the correctly base-paired dNTP and the 3’-OH of the primer

TLS Online TPP Program

#Id: 7790

#Unit 2. Cellular Organization

Nuclear transport receptor

have affinity for FG-repeats on nucleoporins.

TLS Online TPP Program

#Id: 3801

#Unit 5. Developmental Biology

Cell Aggregation & Differentiation is common to all Dictyostelids.

It consists of an interconnected programme of cell movement and cell differentiation.

TLS Online TPP Program

#Id: 6106

#Unit 3. Fundamental Processes

Thymine dimers cause mutations in two ways. (1) Dimers perturb the structure of DNA double helices and interfere with accurate DNA replication. (2) Errors occur during the cellular processes that repair defects in DNA, such as UV-induced thymine dimers To identify chemicals that are converted into mutagens in the liver, the Ames test treats potential indirect mutagens with a mixture of liver extract

TLS Online TPP Program

#Id: 2620

#Unit 13. Methods in Biology

Some restriction endonucleases and their recognition sites.