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TLS Online TPP Program

#Id: 6469

There are 27 of these repeats in the yeast Pol II CTD, 32 in the worm Caenorhabditis elegans, 45 in the fly Drosophila, and 52 in humans.  YSPTSPS repeats in CTD corresponds to the complexity of the genome.


#Unit 3. Fundamental Processes #Eukaryotic Transcription #Part B Pointers
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TLS Online TPP Program

#Id: 8150

#Unit 2. Cellular Organization

Sar1 is the only GTPase switch protein activated at the ER membrane
TLS Online TPP Program

#Id: 8151

#Unit 2. Cellular Organization

Sec12
acts as a GEF factor for Sar1
TLS Online TPP Program

#Id: 8152

#Unit 2. Cellular Organization

After the vesicle coat is complete, the Sec23 coat subunit promotes GTP hydrolysis causes disassembly of the coat.
TLS Online TPP Program

#Id: 8153

#Unit 2. Cellular Organization

A second function of small GTPases in vesicle formation is in the pinching off of a completed vesicle from the parent membrane
TLS Online TPP Program

#Id: 8154

#Unit 2. Cellular Organization

Sar1 GTPase drives the pinching off of COPII vesicles
ARF GTPase drives the pinching off of COPIvesicles
Dynamin GTPase drives the pinching off of clathrin-coated vesicles
TLS Online TPP Program

#Id: 8156

#Unit 2. Cellular Organization

Two different kinds of sorting signals:
Membrane cargo proteins carry cytoplasmic sorting signals
Soluble cargo proteins carry luminal sorting signals