The RNA polymerase I promoter consists of a core promoter and an upstream promoter element (UPE).

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#Id: 3196

#Unit 4. Cell Communication and Cell Signaling

Mutations in three broad classes of genes play key roles in cancer induction: 

Proto-oncogenes genes
Tumor-suppressor genes
Genome maintenance genes

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#Id: 8354

#Unit 2. Cellular Organization

Listeria is a food-borne bacterial pathogen has on its surface a protein ActA, which mimics an NPF that efficiently activates the Arp2/3 complex.

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#Id: 8593

#Unit 2. Cellular Organization

Laminopathies 

Mutation in lamin A

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#Id: 6780

#Unit 3. Fundamental Processes

The mechanism of spacer sequence acquisition is as 

Each new spacer sequence is inserted next to the leader sequence, with the consequence that the array is a temporal record of acquisitions past. The sequence destined to become spacer is, within the phage genome, known as a “proto-spacer” and lies adjacent to a PAM sequence

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#Id: 2270

#Unit 3. Fundamental Processes

Formation of any kind of RNA, from any genome called transcription.