TBP Binds to and Distorts DNA Using a b Sheet Inserted into the Minor Groove

TBP uses an extensive region of  sheet to recognize the minor groove of the TATA element . This is unusual. More typically, proteins recognize DNA using  helices inserted into the major groove of DNA, as we have seen and also for the factor .

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

ZnA and ZnB on RAG1 are regions of the proteins that form zinc fingers, elongated protein domains stabilized by the coordination of a Zn ion.

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#Unit 6. System Physiology – Plant

Glycine decarboxylase GDC multienzyme complex, present in large concentrations in the matrix of plant mitochondria, comprises four proteins, named 

H-protein (a lipoamide-containing polypeptide), 

P-protein (a 200 kDa, homodimer, pyridoxal phosphate-containing protein),

T-protein (a folate-dependent protein), and 

L-protein (a flavin adenine nucleotide–containing protein

Glycine decarboxylase GDC multienzyme complex, present in large concentrations in the matrix of plant mitochondria, comprises four proteins, named 

H-protein (a lipoamide-containing polypeptide), 

P-protein (a 200 kDa, homodimer, pyridoxal phosphate-containing protein),

T-protein (a folate-dependent protein), and 

L-protein (a flavin adenine nucleotide–containing protein

TLS Online TPP Program

#Id: 9676

#Unit 4. Cell Communication and Cell Signaling

Phosphorylation by the mTORC2 kinase complex, of a second serine on

PKB that is not in the activation loop is necessary for maximal PKB activity

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#Unit 4. Cell Communication and Cell Signaling

TGF-β latency

In the Golgi prodomain is proteolytically cleaved from the mature growth factor but remains noncovalently attached even after secretion.

TLS Online TPP Program

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#Unit 4. Cell Communication and Cell Signaling

Human Bcl-2 and worm CED-9 both proteins act as regulators that suppress the apoptotic pathway