SS14 & SS28 both inhibits the secretion of insulin, glucagon, and pancreatic polypeptide and act locally within the pancreatic islets in a paracrine fashion

TLS Online TPP Program

#Id: 639

#Unit 3. Fundamental Processes

The +vely charged acridine dyes or acridine orange are potent mutagens that induce frameshift mutations by Intercalation.

TLS Online TPP Program

#Id: 640

#Unit 3. Fundamental Processes

The +vely charged acridine dyes also causes Slippage and Slippage causes COPY NUMBER MUTATION.

TLS Online TPP Program

#Id: 641

#Unit 3. Fundamental Processes

COPY NUMBER MUTATION are analyzed by simple PCR technique.

TLS Online TPP Program

#Id: 642

#Unit 3. Fundamental Processes

Alkylating agents are chemicals that donate alkyl groups to other molecules as nitrogen mustard, and methyl and ethyl methane sulfonate (MMS and EMS).

TLS Online TPP Program

#Id: 643

#Unit 3. Fundamental Processes

EMS causes ethylation of the bases in DNA at the 7-N and the 6-O positions of G cause G:C → A:T transitions.

TLS Online TPP Program

#Id: 644

#Unit 3. Fundamental Processes

Alkylating agents induce all types of mutations, including transitions, transversions, frameshifts, and even chromosome aberrations.