cas1, cas2, and cas4 required to create protospacer sequences Cas1 is integrase, whereas Cas2 is a ribonuclease. In contrast, of other Cas proteins, Cas6 is involved in expression and processing of the CRISPR cluster and Cas3 in the interference of viral infection.
#Unit 3. Fundamental Processes#mRNA stability, transport, CRISPR, miRNA & siRNA#Part B Pointers