The pre-miRNA liberated by Drosha is exported to the cytoplasm, where the second RNA cleavage reaction, performed by Dicer, takes place. As with Drosha,
Dicer selects its cleavage sites using a measuring, rather than sequence-specific, mechanism.
#Unit 3. Fundamental Processes#mRNA stability, transport, CRISPR, miRNA & siRNA#Part B Pointers