Dicer will act on any dsRNA, regardless of sequence, and will cleave this molecule 22 nucleotides from its end.  The PAZ domain anchors the 3’ terminus of the substrate RNA to position the active sites of the enzyme 22 nucleotides away in a ruler-like fashion

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Axons of retinal ganglion cells  Received and transduced information and carried to the CNS

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Blind spot  There are no visual receptors over the optic disk

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The photosensitive pigment in the rods is called rhodopsin (visual purple).

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Rhodopsin is comprised of: 

Retinal (an aldehyde of vitamin A)

Opsin protein (GPCR)

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Retinal is parallel to the surface of the membrane and is attached to a lysine residue at position 296 in the seventh TM domain.

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#Unit 7. System Physiology – Animal