Heritability- Phenotypic variation that is due to genetic differences. In addition to being polygenic, quantitative characteristics are frequently influenced by environmental factors. 

TLS Online TPP Program

#Id: 6897

#Unit 3. Fundamental Processes

HP1 is recruited to regions in which histone H3 has been methylated at lysine 9, a modification involved in heterochromatin formation. It turns out that HP1 can also interact with Dnmt1, which can promote DNA methylation in the vicinity of HP1 binding. Furthermore, Dnmt1 can directly interact with the methyltransferase responsible for H3K9 methylation, creating a positive feedback loop to ensure continued DNA and histone methylation.

TLS Online TPP Program

#Id: 6898

#Unit 3. Fundamental Processes

TLS Online TPP Program

#Id: 6899

#Unit 3. Fundamental Processes

5-hydroxymethylcytosine (5hmC) is now novel epigenetic marks. The “teneleven translocation 1-3” or Tet1-3 proteinsare DNA TET hydroxylase enzymes that can convert 5mC to 5hmC, and can further convert 5hmC to 5-formylcytosine (5fC) and then 5- carboxylcytosine (5caC) in successive reactions.

TLS Online TPP Program

#Id: 6900

#Unit 3. Fundamental Processes

5-hydroxymethylcytosine (5hmC) is now novel epigenetic marks. The “teneleven traProteins that normally recognize 5mC, such as MeCP2, do not bind to 5hmC, suggesting that generation of 5hmC might serve to reverse methylation-dependent silencing.

TLS Online TPP Program

#Id: 819

#Unit 4. Cell Communication and Cell Signaling

Process of infection, colonization, and reproduction is known as pathogenesis.

TLS Online TPP Program

#Id: 820

#Unit 4. Cell Communication and Cell Signaling

The interactions between organisms from different kingdoms consisting of three phases, referred to as a “zig‐zag‐zig” scheme