E(var) mutations lie in genes whose products are needed to activate gene expression. They include members of the SWI/SNF complex

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#Id: 1667

#Unit 4. Cell Communication and Cell Signaling

Phase III clinical trials are run in expanded volunteer populations.

TLS Online TPP Program

#Id: 1668

#Unit 4. Cell Communication and Cell Signaling

Live, Attenuated Vaccines Microorganisms can be attenuated or disabled so that they lose their ability to cause significant disease but retain their capacity for transient growth within an inoculated host.

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#Id: 1669

#Unit 4. Cell Communication and Cell Signaling

Live attenuated- Measles, Polio (Sabin vaccine), Mumps, Rubella,  Tuberculosis,  and Rotavirus

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#Id: 1670

#Unit 4. Cell Communication and Cell Signaling

Inactivated or “Killed” Vaccines This kills the pathogen, making it incapable of replication

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#Id: 1671

#Unit 4. Cell Communication and Cell Signaling

Inactivated or killed- Cholera, Influenza, Polio (Salk vaccine),  Hepatitis A, Rabies and Covaxin

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#Id: 1672

#Unit 4. Cell Communication and Cell Signaling

Subunit Vaccines

Purified macromolecules derived from the pathogen