In heterozygotes DUPLICATIONS - The pairing and synapsis of homologous regions require that one or both chromosomes loop and twist. 

TLS Online TPP Program

#Id: 2112

#Unit 8. Inheritance Biology

Pseudodominance- Recessive allele owing to a deletion on the homologous chromosome.

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#Id: 2113

#Unit 8. Inheritance Biology

Haploinsufficiency- One copy of the gene is missing, a mutant phenotype is produced.

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#Id: 2114

#Unit 8. Inheritance Biology

Deletions can be detected cytologically by studying the banding patterns in stained chromosomes.

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#Id: 2115

#Unit 8. Inheritance Biology

Large aberrations can be detected by examination of mitotic chromosomes that have been stained with banding agents such as quinacrine or Giemsa.

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#Id: 2116

#Unit 8. Inheritance Biology

hCONDEL- Deletions within the human genome containing sequences that are highly conserved among closely related relatives.

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#Id: 2117

#Unit 8. Inheritance Biology

hCONDELs- responsible for the anatomical and behavioral differences between humans, chimpanzees and other varieties of mammals like ape or monkeys