#Id: 7944
#Unit 2. Cellular Organization
Membrane and soluble secretory proteins synthesized on the rough ER undergo four principal modifications before they reach their final destinations:
(1) Glycosylation in the ER and Golgi complex
(2) Formation of disulfide bonds in the ER
(3) Proper folding of polypeptide chains and assembly of multisubunit proteins in the ER
(4) Specific proteolytic cleavages in the ER, Golgi complex, and secretory vesicles