Class II, but not class I, presentation is inhibited by treatment of the cells with an agent that blocks endocytic processing within the cell (chloroquine).

#Id: 7914

#Unit 2. Cellular Organization

Matrix-targeting sequences

Located at the N-terminus

Usually 20–50 amino acids in length

Rich in hydrophobic amino acids, positively charged basic amino acids (arginine & lysine), and hydroxylated ones (serine and threonine)

Amphipathicity of matrix-targeting sequences is critical to their function

#Id: 7847

#Unit 1. Molecules and their Interaction Relevant to Biology

The two diastereomers of glucose in its "pyranose" form are called the alpha (a) and beta (B) isomers, which differ in the orientation of the OH at C-1

#Id: 2490

#Unit 13. Methods in Biology

SDS (H3C-(CH2 )10 –CH2 -OSO3 – Na+ ) is an anionic detergent used to create negative on sample  On average, one SDS molecule binds for every two amino-acid residues.

#Id: 2478

#Unit 13. Methods in Biology

The most commonly used buffer for separating DNA is TRIS-acetate containing EDTA ( TAE) with a typical pH of 8.3 and used to dissolve the matrix (agarose) as well as the running buffer. 

#Id: 8569

#Unit 1. Molecules and their Interaction Relevant to Biology