Combinatorial diversity: The same heavy chain can combine with different light chain

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#Id: 7327

#Unit 11. Evolution and Behavior

Loci with  multiple alleles

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#Id: 7328

#Unit 11. Evolution and Behavior

X-linked loci

Allele frequency when genotype frequency is given

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#Id: 7329

#Unit 11. Evolution and Behavior

Genetic Disorder

An autosomal recessive condition affects 1 newborn in 10,000 in a random mating population without any  disruptive acting force. What is the approximate expected frequency of carriers in this population?

1 in 1000 newborns

1 in 500 newborns

1 in 100 newborns

1 in 50 newborns

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#Unit 11. Evolution and Behavior

Assumptions—If a population is large, randomly mating, and not affected by  mutation, migration, or natural selection.

Prediction 1 —The allelic frequencies of a population do not change

Prediction 2- The genotypic frequencies stabilize after one  generation in the proportions p2, 2pq, and q2.

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#Unit 11. Evolution and Behavior

The Hardy-Weinberg law, when the assumptions are met, reproduction alone does not alter allelic or genotypic  frequencies.

Hardy-Weinberg law apply to a single locus (di-allelic/ multiple allele).

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#Unit 11. Evolution and Behavior

When a population is in Hardy-Weinberg equilibrium, the genotypic frequencies are determined by the allelic  frequencies.