TIR1 recruits AUX/ IAA proteins to the SCF -TIR1 complex in an auxin-dependent manner. Once recruited by auxin, AUX/IAA proteins are ubiquitinated by the E3 ligase activity of the SCF-TIR1 complex, which marks the protein for destruction by the 26S proteasome.
#Unit 6. System Physiology – Plant#Auxin/GA/Cytokinin#Part B Pointers