TIR1 recruits AUX/ IAA proteins to the SCF -TIR1 complex in an auxin-dependent manner. Once recruited by auxin, AUX/IAA proteins are ubiquitinated by the E3 ligase activity of the SCF-TIR1 complex, which marks the protein for destruction by the 26S proteasome.

TLS Online TPP Program

#Id: 10330

#Unit 4. Cell Communication and Cell Signaling

The idea behind CARs was to engineer the T-cell receptor to trigger activation of ZAP70 in response to the presence of a tumor-specific antigen rather than the MHC peptide complex. 

TLS Online TPP Program

#Id: 10331

#Unit 4. Cell Communication and Cell Signaling

TLS Online TPP Program

#Id: 10332

#Unit 4. Cell Communication and Cell Signaling

TLS Online TPP Program

#Id: 10333

#Unit 4. Cell Communication and Cell Signaling

TLS Online TPP Program

#Id: 10334

#Unit 4. Cell Communication and Cell Signaling

B cell is type of lymphocyte.

B cell synthesized and maturation in bone marrow.

TLS Online TPP Program

#Id: 10335

#Unit 4. Cell Communication and Cell Signaling