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The capacities the sperm gain are those for:
recognizing the cues that will guide them to the egg
undergoing the acrosome reaction
fusing with the egg cell membrane

#Unit 5. Developmental Biology #Fertilization #Part B Pointers
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TLS Online TPP Program

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#Unit 5. Developmental Biology

T1 cells are mIgMhi, mIgD -/lo, CD21-, CD23-, CD24+, and CD93+. 
T2 cells differ from T1 cells in having higher levels of mIgD and in expressing CD21 and CD23. 

TLS Online TPP Program

#Id: 7248

#Unit 5. Developmental Biology

T2 cells also express BAFF-R, the receptor for the B-cell survival factor BAFF, whose expression is dependent on signals received through the BCR. 
As B cells differentiate from the transitional T2 state to full maturity, they raise their levels of mIgD still further, while reducing the expression of mIgM. They also cease to express CD24 and CD93.

TLS Online TPP Program

#Id: 7249

#Unit 5. Developmental Biology


TLS Online TPP Program

#Id: 7250

#Unit 5. Developmental Biology

T-dependent (TD) response


TLS Online TPP Program

#Id: 7251

#Unit 5. Developmental Biology

T-independent response


TLS Online TPP Program

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#Unit 5. Developmental Biology

B-Cell Activation


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