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The capacitated sperm are also able to detect and respond to picomolar amounts of the hormone progesterone, which is secreted by the cumulus cells surrounding the egg



#Unit 5. Developmental Biology #Fertilization #Part B Pointers
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TLS Online TPP Program

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#Unit 7. System Physiology – Animal

Increase in intracellular cAMP facilitates the opening of L channels, increasing ICa and the rapidity of the depolarization phase of the impulse.


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#Unit 7. System Physiology – Animal

When the cholinergic vagal fibers to nodal tissue are stimulated, the membrane becomes hyperpolarized and the slope of the prepotentials is decreased


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#Unit 7. System Physiology – Animal

Acetylcholine (ACh), released from parasympathetic nerve fibers, activates muscarinic (M2) receptors in the SA node.


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#Unit 7. System Physiology – Animal

activation of the M2 receptors decreases cyclic adenosine 3′,5′-monophosphate (cAMP) in the cells, and this slows the opening of Ca 2+ channels.


TLS Online TPP Program

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#Unit 7. System Physiology – Animal

βγ subunit of a G protein, open a special set of K + channels. The resulting IKAch slows the depolarizing effect of Ih .


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#Unit 7. System Physiology – Animal


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