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Mutations in either Juno or Izumo block fertilization

#Unit 5. Developmental Biology #Fertilization #Part B Pointers
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#Unit 11. Evolution and Behavior

PreCambrian- Earliest eukaryotes and multicellular eukaryotes

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#Unit 4. Cell Communication and Cell Signaling

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#Unit 4. Cell Communication and Cell Signaling

TGF-β1 and TGF-β3 contain RGD motif that binds to integrins.

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#Unit 3. Fundamental Processes

Thymine dimers cause mutations in two ways. (1) Dimers perturb the structure of DNA double helices and interfere with accurate DNA replication. (2) Errors occur during the cellular processes that repair defects in DNA, such as UV-induced thymine dimers To identify chemicals that are converted into mutagens in the liver, the Ames test treats potential indirect mutagens with a mixture of liver extract

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#Unit 3. Fundamental Processes

DnaA-ATP in an extended multimeric state promoted by the accessory protein DiaA, which stimulates cooperative binding of DnaA.
DnaA-ATP binds cooperatively to form a helical central core around which oriC DNA is wrapped.

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