Nurturing Life Sciences
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#Unit 5. Developmental Biology
B-Cell Activation
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Generation of antibodies to T-dependent antigens
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Properties of thymus-dependent and thymus-independent antigens
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B cells can be negatively signaled through CD22 and FcγRIIb a receptor that recognizes the presence of IgG containing immune complexes in the blood.
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On the left side of Hensen’s node, Sonic hedgehog (Shh) activates Cerberus, which stimulates BMPs to induce the expression of Nodal