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TLS Online TPP Program

#Id: 7691

                                             bab Motif

These motifs are generally found in right handed helix above the plane of the beta sheet

Almost all the proteins containing parallel beta sheets have this motif. 

The helix is generally not seen below the plane of beta sheets                                           

#Unit 1. Structure and Function of Biomolecules #Secondary structure #Part B Pointers
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TLS Online TPP Program

#Id: 8587

#Unit 2. Cellular Organization

In the cytoplasm, KASH proteins can bind directly to microfilaments and indirectly to microtubules and Ifs through association with motor proteins and plakins, respectively.
TLS Online TPP Program

#Id: 8588

#Unit 2. Cellular Organization

TLS Online TPP Program

#Id: 8589

#Unit 2. Cellular Organization

Lamins are reversibly disassembled by phosphorylation during mitosis
TLS Online TPP Program

#Id: 8590

#Unit 2. Cellular Organization

Mitotic CDKs drive phosphorylation of lamins A, B, and C results in disassembly of the intermediate filament lattice into lamin dimers.
TLS Online TPP Program

#Id: 8591

#Unit 2. Cellular Organization

Due to C-terminal prenylation of lamin B, 
lamin B dimers remain associated with the nuclear
membrane
TLS Online TPP Program

#Id: 8592

#Unit 2. Cellular Organization

During telophase, de-phosphorylation by specific phosphatases promotes lamin reassembly, which is critical to re-formation of a nuclear envelope around the daughter chromosomes.