Greek Key Motif

Made-up of beta-sheets

Four adjacent antiparallel strands linked by loops

Three anti-parallel beta sheets are connected 3 loops

The pattern is similar to ornamental pattern used I ancient Greece, therefore called as Greek Key motif

TLS Online TPP Program

#Id: 5711

#Unit 7. System Physiology – Animal

Somatotropes—human growth hormone

promotes growth of the entire body by affecting protein formation, cell multiplication, and cell differentiation.

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#Id: 5712

#Unit 7. System Physiology – Animal

Principal signaling pathway activated by the growth hormone- JAK–STAT

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#Id: 5713

#Unit 7. System Physiology – Animal

Somatostatin (somatotropin release–inhibiting hormone) -hypothalamus Inhibit growth hormone secretion.

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#Id: 5714

#Unit 7. System Physiology – Animal

Somatostatin binds membrane receptor, which is coupled to Galpha i protein.

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#Id: 5715

#Unit 7. System Physiology – Animal

Before puberty, Growth hormone excess causes gigantism

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#Id: 5716

#Unit 7. System Physiology – Animal

After puberty, Growth hormone excess causes acromegaly