Membrane and soluble secretory proteins synthesized on the rough ER undergo four principal modifications before they reach their final destinations: 

(1) Glycosylation in the ER and Golgi complex

(2) Formation of disulfide bonds in the ER

(3) Proper folding of polypeptide chains and assembly of multisubunit proteins in the ER

(4) Specific proteolytic cleavages in the ER, Golgi complex, and secretory vesicles

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#Unit 2. Cellular Organization

Golgi apparatus is a major site of carbohydrate synthesis, as well as a sorting and dispatching station for proteins products.

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#Unit 2. Cellular Organization

In animal cells,

Most of the glycosaminoglycans of the extracellular matrix are synthesized in golgi apparatus.

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#Unit 2. Cellular Organization

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Three major types of coated vesicles involved in protein trafficking:

1. COPII vesicles

2. COPI vesicles 

3. Clathrin-coated vesicles

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Anterograde transport

COPII vesicles = ER to Golgi

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#Unit 2. Cellular Organization

Anterograde transport through the golgi occurs by cisternal maturation