Nurturing Life Sciences
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NLSs were first discovered through the analysis of mutations of the gene for large T-antigen encoded by simian virus 40 (SV40).
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#Unit 4. Cell Communication and Cell Signaling
ETI are usually stronger than PTI and cause hypersensitive reaction or apoptosis of tissue
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Effectorâencoding genes or avirulence (Avr) genes, found in pathogen as the Pseudomonas produces AvrPto effector causes avirulence.
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Tomato (Solanum lycopersicum) carry Pto resistance gene so Pseudomonas infection resistance
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A successful pathogen overcomes PTI and has effectors that evade R proteinâmediated detection.
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ETI invasion by pathogen causes selection of novel R gene variants that can recognize other pathogen effector molecules and then activate defense.
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Race between effector and ETI evolution is an example of coevolution between plants and pathogens