NLSs were first discovered through the analysis of mutations of the gene for large T-antigen encoded by simian virus 40 (SV40).

TLS Online TPP Program

#Id: 1620

#Unit 4. Cell Communication and Cell Signaling

TLR4 is unique in binding both MyD88 (when it is in the plasma membrane, signaling its endocytosis) and TRIF (when it is in endosomes, after internalization).

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#Id: 4758

#Unit 5. Developmental Biology

skn-1-deficient embryos make extra hypodermal (skin) & body wall tissue.

TLS Online TPP Program

#Id: 2754

#Unit 13. Methods in Biology

An AFLP is detected as a differential mobility of an amplified DNA fragment; AFLPs, therefore, behave as codominant markers during inheritance.

TLS Online TPP Program

#Id: 7899

#Unit 2. Cellular Organization

Only 22 tRNAs are required for mitochondrial protein synthesis. The normal codon–anticodon pairing rules are relaxed in mitochondria, so that many tRNA molecules recognize any one of the four nucleotides in the third (wobble) position, allowing four codons to be recognized by a single tRNA.

TLS Online TPP Program

#Id: 7895

#Unit 2. Cellular Organization

Vertebrate mtDNAs encode 2 rRNAs, 22 tRNAs, and 13 proteins involved in electron transport and ATP synthesis.