Leber’s hereditary optic neuropathy

caused by a missense mutation in the mtDNA gene

encoding subunit 4 of the NADH-CoQ reductase

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#Id: 4838

#Unit 13. Methods in Biology

It is represented by Greek letter α (alpha) and is also known as alpha level.

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#Unit 13. Methods in Biology

Usually, the significance level or the probability of type i error is set to 0.05(5%), assuming that it is satisfactory to have a 5% probability of inaccurately rejecting the null hypothesis.

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#Unit 13. Methods in Biology

A type II error appears when the null hypothesis is false but mistakenly fails to be refused.

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#Id: 4841

#Unit 13. Methods in Biology

A type II error is also known as false negative (where a real hit was rejected by the test and is observed as a miss), in an experiment checking for a condition with a final outcome of true or false.

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#Unit 13. Methods in Biology

A type II error is assigned when a true alternative hypothesis is not acknowledged. In other words, an examiner may miss discovering the bear when in fact a bear is present (hence fails in raising the alarm).

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#Unit 13. Methods in Biology

Again, H0, the null hypothesis, consists of the statement that, “There is no bear”, wherein, if a wolf is indeed present, is a type II error on the part of the investigator.