Each sarcomere contains two major types of filaments: 

Thick filaments (myosin II)

Thin filaments (actin and associated proteins)

TLS Online TPP Program

#Id: 523

#Unit 2. Cellular Organization

Exon Sequences Under Positive Selection Vary but Introns Are Conserved

TLS Online TPP Program

#Id: 2833

#Unit 13. Methods in Biology

The peptide or protein (known as a ‘ tag’) can be placed at the N- or C-terminal ends and provides a means for the fusion protein to be selectively purified from the cell extract by affinity chromatography.

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#Id: 5907

#Unit 3. Fundamental Processes

In the case of a DNA helicase that functions on the lagging-strand template of the replication fork, the polarity is 5’->3’ to allow the DNA helicase to proceed toward the duplex region of the replication fork The PhiX system, named originally for phage X174, requires an initiation complex consisting of additional components, called the primosome. This system is used when damage causes the replication fork to collapse and it must be restarted.

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#Id: 1494

#Unit 4. Cell Communication and Cell Signaling

DNA damage leads to phosphorylation of MDM2, which inhibits its ability to promote p53 degradation allowing p53 levels to increase.

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#Id: 2732

#Unit 12. Applied Biology