Parkinson’s disease is caused by mutations in two gene encoding proteins that can mediate mitophagy:

PINK1 (a kinase)

Parkin (E3 ubiquitin ligase)

TLS Online TPP Program

#Id: 548

#Unit 2. Cellular Organization

Outer membrane of gram negative provides barrier to certain antibiotics, lysozyme, detergents, heavy metals, bile salts, etc.

TLS Online TPP Program

#Id: 6782

#Unit 3. Fundamental Processes

The protospacer adjacent motif (or PAM for short) is a short DNA sequence (usually 2-6 base pairs in length) that follows the DNA region targeted for cleavage by the CRISPR system, such as CRISPR-Cas9. The PAM is required for a Cas nuclease to cut and is generally found 3-4 nucleotides downstream from the cut site

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#Id: 7209

#Unit 5. Developmental Biology

Corticosteroids and prostaglandins can also decrease expression of class II MHC molecules.

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#Id: 1922

#Unit 4. Cell Communication and Cell Signaling

B-10 B cells release the interleukin IL-10 upon antigenic stimulation, and may serve to reduce inflammation during an ongoing immune response.

TLS Online TPP Program

#Id: 8901

#Unit 2. Cellular Organization

Condensin association with chromosomes is facilitated by mitotic CDKs and Aurora B, which phosphorylate histone H2A, allowing condensins to bind chromatin.