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TLS Online TPP Program

#Id: 8341

Two major classes of actin-nucleating proteins:

1. Formins nucleate the assembly of unbranched filaments 

2. Arp2/3 complex nucleates the assembly of branched actin networks

#Unit 2. Cellular Organization #MICROFILAMENTS #Part B Pointers
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TLS Online TPP Program

#Id: 1339

#Unit 4. Cell Communication and Cell Signaling

The function of a growth factor-  stabilize receptor dimerization
TLS Online TPP Program

#Id: 1340

#Unit 4. Cell Communication and Cell Signaling

HER1 & HER4, can form stable homodimers after binding a growth factor.
TLS Online TPP Program

#Id: 1341

#Unit 4. Cell Communication and Cell Signaling

HER2 can signal only by forming heterodimers with ligand-bound HER1, HER3, or HER4
TLS Online TPP Program

#Id: 1342

#Unit 4. Cell Communication and Cell Signaling

HER3 lacks a functional kinase domain
TLS Online TPP Program

#Id: 1343

#Unit 4. Cell Communication and Cell Signaling

RAS is a small monomeric G-proteins.
TLS Online TPP Program

#Id: 1344

#Unit 4. Cell Communication and Cell Signaling

RAS is connected to the membrane by a prenylated (lipid) tail.