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TLS Online TPP Program

#Id: 8389

Smooth muscle contraction is regulated by the cycling of myosin II between on and off states.

#Unit 2. Cellular Organization #Myosin & Muscle Contraction #Part B Pointers
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TLS Online TPP Program

#Id: 7901

#Unit 2. Cellular Organization

Deletions in mtDNA cause another set of diseases:
Chronic progressive external ophthalmoplegia
Kearns–Sayre syndrome
TLS Online TPP Program

#Id: 7902

#Unit 2. Cellular Organization

Single mutation in the TΨCG loop of the mitochondrial lysine tRNA
“Ragged-red” muscle fibers & uncontrolled jerky movements
TLS Online TPP Program

#Id: 7903

#Unit 2. Cellular Organization

Mitochondrial fusion and fission are mediated by a set of GTPase enzymes:

Mitochondrial fusion -MFN1/2 & OPA1

Mitochondrial fission- DRP1
TLS Online TPP Program

#Id: 7904

#Unit 2. Cellular Organization
TLS Online TPP Program

#Id: 7905

#Unit 2. Cellular Organization

Mitophagy provides Mitochondrial Quality Control
TLS Online TPP Program

#Id: 7906

#Unit 2. Cellular Organization

When the environment of a cell has inadequate oxygen, enzymatic modification of proteins on the outer mitochondrial membrane induces mitophagy.