TLS Online TPP Program

#Id: 8459


Five types of constraints affect the stability of an  helix: 
(1) the intrinsic propensity of an amino acid residue to form an  helix; 
(2) the interactions between R groups, particularly those spaced three (or four) residues apart; 
(3) the bulkiness of adjacent R groups; 
(4) the occurrence of Pro and Gly residues; and 
(5) interactions between amino acid residues at the ends of the helical segment and the electric dipole inherent to the  helix.

#Unit 1. Molecules and their Interaction Relevant to Biology #Conformation of proteins #Part B Pointers