Nurturing Life Sciences
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#Unit 3. Fundamental Processes
DNA polymerase “grips” the template and the incoming nucleotide when a correct base pair is made via Arg, Lys and Tyr residue in its alpha helix
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Base-pair geometry and the complementarity between the bases cannot reach the extraordinarily high levels of accuracy
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Approximately one mistake in every 1010 bp added due to keto-enol tautomerism.
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oriC must be fully methylated.
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DnaA-ATP binds to short repeated sequences and forms an oligomeric com plex that melts DNA