Nurturing Life Sciences
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#Unit 3. Fundamental Processes
For the synthesis of telomere, Only dGTP and dTTP are needed for the activity.
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The telomerase is a large ribonucleoprotein that consists of a templating RNA which is encoded by TLC1 in yeast, hTERC in humans.
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Telomerase protein component with catalytic activity is encoded by EST2 in yeast, hTERT in humans
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The RNA component is typically short 159 bases long in Tetrahymena, and 451 bases long in humans, though 1.3 kb in yeast
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EST proteins regulates number of repeats in RNA component for telomere lengths.
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