Polyglutamylation and polyglycylation are likely mutually exclusive, so they would not normally occur at the same time & both can enhance microtubule stability,

TLS Online TPP Program

#Id: 6694

#Unit 3. Fundamental Processes

Editing involves the transfer of Us into the gap in the message.This process is catalyzed by the enzyme 3’ terminal uridylyl transferase (TUTase).

TLS Online TPP Program

#Id: 6695

#Unit 3. Fundamental Processes

Deamination of the human apolipoprotein B mRNA takes place by an enzyme called APOBEC1

TLS Online TPP Program

#Id: 6696

#Unit 3. Fundamental Processes

APOBEC3G (A3G)—is a potent inhibitor of infection by a range of retroviruses, including HIV. deaminates Cs to produce Us in that DNA strand, leading to hypermutation at levels the virus cannot accommodate, or even to destruction of the damaged strand by DNA glycosylase and apurinic apyrimidinic endonuclease

TLS Online TPP Program

#Id: 6697

#Unit 3. Fundamental Processes

Wild-type HIV produces a protein called Vif (viral infectivity factor) that directs proteosomal degradation of the A3G enzyme

TLS Online TPP Program

#Id: 6698

#Unit 3. Fundamental Processes

TLS Online TPP Program

#Id: 6699

#Unit 3. Fundamental Processes