Substrate-binding could cause a conformational change to take place in the enzyme and reveal an inhibitor binding site, or the inhibitor could bind directly to the enzyme-bound substrate. 

TLS Online TPP Program

#Id: 3504

#Unit 2. Cellular Organization

In multicellular eukaryotes most genes are interrupted, and the introns are usually much longer than exons, so genes are considerably larger than their coding regions.

TLS Online TPP Program

#Id: 9979

#Unit 4. Cell Communication and Cell Signaling

Active Wnt signaling leads to the secretion of Notum.

TLS Online TPP Program

#Id: 3009

#Unit 3. Fundamental Processes

Replication requires a helicase to separate the strands of DNA using energy provided by hydrolysis of ATP.

TLS Online TPP Program

#Id: 3330

#Unit 3. Fundamental Processes

Central to transcription-coupled repair in eukaryotes is the general transcription factor TFIIH.

TLS Online TPP Program

#Id: 10379

#Unit 4. Cell Communication and Cell Signaling