A system to unambiguously describe the configurations of molecules with more than one asymmetric center was devised in 1956 by Robert Cahn, Christopher Ingold, and Vladimir Prelog. In the Cahn–Ingold– Prelog or RS system

TLS Online TPP Program

#Id: 8540

#Unit 2. Cellular Organization

Dynein-related transport requires dynactin, that links dynein to its cargo

TLS Online TPP Program

#Id: 8572

#Unit 2. Cellular Organization

Soft keratins, or cytokeratins, are found in epithelial cells and make up the skin.

TLS Online TPP Program

#Id: 8573

#Unit 2. Cellular Organization

In all epithelia, keratin filaments associate with: Desmosomes (cell–cell contact)

Hemidesmosomes (cell–matrix contact)

TLS Online TPP Program

#Id: 8574

#Unit 2. Cellular Organization

when defective keratins are expressed in the basal cell layer of the epidermis, they produce a disorder called epidermolysis bullosa simplex

TLS Online TPP Program

#Id: 8575

#Unit 2. Cellular Organization

Vimentin, found in mesenchymal cells;

GFAP (glial fibrillary acidic protein), found in glial cells

Desmin, found in muscle cells

TLS Online TPP Program

#Id: 8576

#Unit 2. Cellular Organization

In smooth muscle, desmin filaments link cytoplasmic dense bodies to the plasma membrane to ensure that cells resist overstretching.