The Cip/Kip family members bind to cyclin-bound CDKs and block the activity of cyclin D-, E-, A-, and B-containing complexes.

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In AV3V region, two structures called osmoreceptors:

subfornical organ

organum vasculosum

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The anterior pituitary secretes six peptide hormones: 

TSH, FSH, LH, GH, prolactin, & ACTH

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Thyrotropin-releasing hormone (TRH) 

Tripeptide

Stimulates secretion of TSH by thyrotropes

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Corticotropin-releasing hormone (CRH) 

Stimulates secretion of ACTH by corticotropes

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ACTH (corticotropin) 

controls the secretion of cortisol by the activation of adenylyl cyclase via Galpha s.