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TLS Online TPP Program

#Id: 8623

SCF and APC/C are multisubunit ubiquitin-protein ligases that belong to the RING finger family of ubiquitin-protein ligases.

#Unit 2. Cellular Organization #CELL CYCLE #Part B Pointers
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TLS Online TPP Program

#Id: 8932

#Unit 2. Cellular Organization
TLS Online TPP Program

#Id: 8933

#Unit 2. Cellular Organization
TLS Online TPP Program

#Id: 8934

#Unit 2. Cellular Organization

Spindle assembly checkpoint pathway is active until every single kinetochore has attached properly to spindle microtubules
TLS Online TPP Program

#Id: 8935

#Unit 2. Cellular Organization
TLS Online TPP Program

#Id: 8936

#Unit 2. Cellular Organization

When a kinetochore is unattached, the outer kinetochore component Knl1 is phosphorylated by the checkpoint kinase Mps1.
TLS Online TPP Program

#Id: 8937

#Unit 2. Cellular Organization

Phosphorylated Knl1 binds the checkpoint protein kinase Bub1-Bub3 and checkpoint protein BubR1. These three proteins, recruit the Mad1-Mad2 complex to the kinetochore.