Intrinsically disordered proteins lack a hydrophobic core, and have high densities of charged amino acid residues such as Lys, Arg, and Glu. Pro residues are also prominent, as they tend to disrupt ordered structures.

TLS Online TPP Program

#Id: 9425

#Unit 11. Evolution and Behavior

TLS Online TPP Program

#Id: 1481

#Unit 4. Cell Communication and Cell Signaling

Let-7 miRNAs down-regulate the translation of Ras. Thus in the absence of the miRNAs, Ras is constitutively overproduced, contributing to tumorigenesis.

TLS Online TPP Program

#Id: 7021

#Unit 5. Developmental Biology

The adult stem cell is housed in and controlled by its own adult stem cell niche, which regulates stem cell self-renewal, survival, and differentiation of those progeny that leave the niche.

TLS Online TPP Program

#Id: 7479

#Unit 4. Cell Communication and Cell Signaling

IgG efficiently opsonizes pathogens for engulfment by phagocytes and activates the complement system. The affinity of the individual antigen binding sites for their antigen is therefore critical for the effectiveness of these antibodies, and most of the B cells expressing these classes have been selected in the germinal centers for their increased affinity for antigen after somatic hyper mutation.

TLS Online TPP Program

#Id: 10342

#Unit 4. Cell Communication and Cell Signaling