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TLS Online TPP Program

#Id: 8847


When CDK activity is low= helicases are loaded in G1
When CDK activity is high= helicases are activated in
S, G2 & M

#Unit 2. Cellular Organization #Steps in cell cycle, regulation and control of cell cycle #Part B Pointers
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TLS Online TPP Program

#Id: 6768

#Unit 3. Fundamental Processes

In nonsense mediated decay  in the addition of multiple lysines to the end of the protein (AAA is the codon for lysine) and stalling of the ribosome at the end of the mRNA. 

TLS Online TPP Program

#Id: 6769

#Unit 3. Fundamental Processes


TLS Online TPP Program

#Id: 6770

#Unit 3. Fundamental Processes

Upf1 is the first NMD protein to act, binding to the terminating ribosome—specifically to its release factor complex.

TLS Online TPP Program

#Id: 6771

#Unit 3. Fundamental Processes

nonstop-mediated decay rescues ribosomes that translate mRNAs that lack a stop codon. When an mRNA lacking a stop codon is translated, the ribosome translates through the poly-A tail This results 



TLS Online TPP Program

#Id: 6772

#Unit 3. Fundamental Processes


TLS Online TPP Program

#Id: 6773

#Unit 3. Fundamental Processes

The cap binding CBP20/80 complex appears to directly bind to the mRNA export machinery (the TREX complex)

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