The Aurora protein kinase family members Aurora A and Aurora B and their associated regulatory factors sense kinetochores that are not under tension and sever these microtubule attachments

TLS Online TPP Program

#Id: 460

#Unit 2. Cellular Organization

PHD and the Tudor domain also recognizes methyl-lysine.

TLS Online TPP Program

#Id: 461

#Unit 2. Cellular Organization

Parity rules were given by Erwin Chargaff

I. Rule of complementarity 

II. Rule of Equal amount applies more closely to introns than to exons

III. Cluster rule – Purines in nontemplate strand applies more closely to Exons

TLS Online TPP Program

#Id: 462

#Unit 2. Cellular Organization

GC Rule- GC content tends to be greater in exons than in introns

TLS Online TPP Program

#Id: 463

#Unit 2. Cellular Organization

Exons are the sequences which essentially encodes for functional and properly folded polypeptide or RNA molecule

TLS Online TPP Program

#Id: 464

#Unit 2. Cellular Organization

Introns are nucleotide sequence which cannot encode functional proteins or polypeptides or introns do not have a sequence-specific function.

TLS Online TPP Program

#Id: 465

#Unit 2. Cellular Organization

Introns have negative Fold Potential i.e. potential to form stem loop.