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TLS Online TPP Program

#Id: 8912

When all the kinetochores have properly attached to spindle microtubules, APC/CCdc20 directs ubiquitinylation of securin and mitotic cyclins

#Unit 2. Cellular Organization #CELL CYCLE #Part B Pointers
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TLS Online TPP Program

#Id: 9478

#Unit 4. Cell Communication and Cell Signaling

SOCS box, 
Recruits E3 ubiquitin ligases that polyubiquitinylate the receptor and the JAK kinase & marks the proteins for destruction by a proteasome
TLS Online TPP Program

#Id: 9479

#Unit 4. Cell Communication and Cell Signaling

SOCS-1, binds to the critical phosphotyrosine in the activation loop of an activated JAK2 kinase, inhibiting its catalytic activity
TLS Online TPP Program

#Id: 9480

#Unit 4. Cell Communication and Cell Signaling
TLS Online TPP Program

#Id: 9481

#Unit 4. Cell Communication and Cell Signaling
TLS Online TPP Program

#Id: 9604

#Unit 4. Cell Communication and Cell Signaling

NGF, PDGF, FGF, EGF, insulin are RTK ligands, which trigger proliferation of cells.
TLS Online TPP Program

#Id: 9605

#Unit 4. Cell Communication and Cell Signaling

The cytosolic domain of RTKs contains an intrinsic protein tyrosine kinase domain.