In S. cerevisiae, during interphase and early mitosis, Cdc14 is sequestered and inactivated in the nucleolus. 

TLS Online TPP Program

#Id: 8365

#Unit 2. Cellular Organization

Three classes of myosins:

Myosin I

Myosin II

Myosin V

TLS Online TPP Program

#Id: 8366

#Unit 2. Cellular Organization

Myosin I

single head domain

Function- Membrane association, endocytosis

TLS Online TPP Program

#Id: 8367

#Unit 2. Cellular Organization

Myosin II

Two heads and assembles into bipolar filaments

Small and non-processive

Function- Contraction

TLS Online TPP Program

#Id: 8368

#Unit 2. Cellular Organization

Myosin V

Two heads but does not assemble into filaments

Large and processive

Function- Organelle transport

TLS Online TPP Program

#Id: 8369

#Unit 2. Cellular Organization

The length of the myosin II neck domain determines the rate of movement.

TLS Online TPP Program

#Id: 8370

#Unit 2. Cellular Organization

In the absence of ATP, the myosin head is firmly attached to the actin filament.