3 separate TGF-β receptor proteins participate in binding TGF-β and activating signaling:

RI, RII, and RIII

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#Unit 3. Fundamental Processes

A regulatory site that binds more negative regulators than positive regulators to control transcription is called a silencer.

TLS Online TPP Program

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#Unit 2. Cellular Organization

Function of the ER:

most eukaryotic cells is to sequester Ca2+ from the cytosol (High concentration of Ca2+-binding proteins in the ER facilitates Ca2+ storage)

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#Unit 4. Cell Communication and Cell Signaling

Activated dimeric MAP kinase induces transcription of the c-fos gene by directly activating TCF, and indirectly activating SRF.

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#Unit 11. Evolution and Behavior

Nonrandom Mating - Nonrandom mating are two type,

1. Positive assortative mating - Like individuals to mate.

2. Negative assortative mating - Unlike individuals to mate

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#Unit 2. Cellular Organization

Local genome alteration, termed kataegis involves activation-induced deaminase (AID)

Chromothripsis entire chromosomes or large parts thereof are shattered (thripsis in Greek means “shattering”) and stitched together again in what appears to be a random manner, leading to dozens or sometimes even hundreds of rearrangements.