Nurturing Life Sciences
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Konrad Lorenz
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#Unit 3. Fundamental Processes
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The MCM proteins, once activated, are required for elongation as well as for initiation.
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The MCM proteins continue to function at the two bidirectional replication forks as the replication helicase.
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In yeast, the combined action of Cdc6, Cdtl, and the MCM proteins provides the licensing function.
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The replisome exists only as a protein complex associated with the particular structure that DNA takes at the replication fork.