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#Unit 11. Evolution and Behavior #Sexual Selection #Part B Pointers
More Pointers
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#Id: 7369

#Unit 5. Developmental Biology

First zygotic genes is Gap genes. Mutations in them cause gaps in the segmentation pattern.


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#Id: 7370

#Unit 5. Developmental Biology

Gap genes encode transcription factors, and differing combinations and concentrations of gap gene proteins regulate the transcription of pair-rule genes, which divide the embryo into periodic units.


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#Unit 5. Developmental Biology

The transcription factors encoded by the pair-rule genes activate the segment polarity genes, whose mRNA and protein products divide the embryo into 14-segment-wide units, establishing the periodicity of the embryo. 


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#Unit 5. Developmental Biology

Major genes affecting segmentation pattern 

1.Gap genes                 2. Pair rule genes(primary)           3. Segment polarity genes      

Kruppel (Kr)                    hairy(h)                                             engrailed (en)

knirps (kni)                      even skipped(eve)                           wingless (wg)

hunchback (hb)              runt(run)                                           cubitus interruptus(ci) 

giant (gt)                          Pair rule genes (secondary)           hedgehog(hh)

tailless (til)                       fushi tarazu (ftz)                              fused (fu)

huckebein (hkb)              odd paired (opa)                             armadillo (arm)

buttonhead (btd)            odd skipped (odd)                          patched (ptc)

empty spiracles (ems)    sloppy paired (slp)                          gooseberry (gsb)

orthodenticle (otd)         paired (prd)                                      pangolin (pan

TLS Online TPP Program

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#Unit 5. Developmental Biology

At the same time, the protein products of the gap, pair-rule, and segment polarity genes interact to regulate another class of genes, the homeotic selector genes, whose transcription determines the developmental fate of each segment


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#Id: 7374

#Unit 5. Developmental Biology

Gurken protein is a member of the EGF (epidermal growth factor) family, and Torpedo encodes a homologue of the vertebrate EGF receptor.