Binding resembles the insertion of a two-pronged “plug” the phosphotyrosine and isoleucine side chains

of the peptide into a two-pronged “socket” in the SH2 domain.

TLS Online TPP Program

#Id: 4736

#Unit 5. Developmental Biology

The zygote of C. elegans exhibits rotational holoblastic cleavage.

TLS Online TPP Program

#Id: 9945

#Unit 4. Cell Communication and Cell Signaling

The merozoites infect red blood cells, which eventually rupture, releasing more merozoites. 

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#Id: 1220

#Unit 7. System Physiology – Animal

When extracellular Ca2+ is decreased decreased Ca2+ binding to the receptor stimulates PTH secretion

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#Id: 4549

#Unit 12. Applied Biology

TLS Online TPP Program

#Id: 6302

#Unit 3. Fundamental Processes

During abortive Transcription, RNA Polymerase Remains Stationary and Pulls Downstream DNA into Itself RNA polymerase produces and releases short RNA transcripts of 10 nucleotides (abortive synthesis) before escaping the promoter, 

 

During abortive Transcription, RNA Polymerase Remains Stationary and Pulls Downstream DNA into Itself

RNA polymerase produces and releases short RNA transcripts of 10 nucleotides (abortive synthesis) before escaping the promoter, entering the elongation phase, and synthesizing the proper transcript. It has long been unclear how the enzyme’s active site translocates along the DNA template during initial abortive cycles of transcription. Three general models were proposed:- “transient excursion”, “Inchworming”, “Scrunching”