#Id: 5050
#Unit 3. Fundamental Processes
DnaA is an ATP-binding protein.
The first stage in initiation is binding of the DnaA-ATP protein complex to the fully methylated oriC sequence.
This takes place in association with the inner membrane. DnaA is in the active form only when bound to ATP.
DnaA has intrinsic ATPase activity that hydrolyzes ATP to ADP and thus inactivates itself when the initiation stage ends.