Monomeric state of the EGF receptor,

activation loop is situated in the active site of the kinase near the interface of the N and C lobes, blocking the site’s activity; in this way the kinase is maintained in the inactive or “off” state

TLS Online TPP Program

#Id: 5544

#Unit 7. System Physiology – Animal

The thick ascending limb has a sodium-hydrogen counter-transport

TLS Online TPP Program

#Id: 3208

#Unit 4. Cell Communication and Cell Signaling

Mutations in three broad classes of genes play key roles in cancer induction:
Proto-oncogenes genes
Tumor-suppressor genes
Genome maintenance genes

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#Id: 9837

#Unit 6. System Physiology – Plant

COP1 is found in the nucleus in the dark and in the cytoplasm in the light. COP1 movement into the nucleus in the dark requires the COP9 signalosome (CSN) complex

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#Id: 3539

#Unit 2. Cellular Organization

The chloroplast genome is generally similar to that of mitochondria, except that there are more genes.

TLS Online TPP Program

#Id: 8864

#Unit 2. Cellular Organization

Defects of cohesin’s gene expression regulation function are the cause of a group of diseases collectively called cohesinopathies.