Processes That Kill Phagocytosed Microbes

Agents include antimicrobial proteins and peptides, low pH, hydrolytic enzymes including lysozyme and proteases activated by the increasing acidity of the phagolysosomes, and specialized molecules that mediate oxidative attack.

TLS Online TPP Program

#Id: 1330

#Unit 4. Cell Communication and Cell Signaling

Phospholipase C cleaves PI(4,5)P2, generating two second messengers:  IP3 and DAG

TLS Online TPP Program

#Id: 1331

#Unit 4. Cell Communication and Cell Signaling

The principal function of DAG is to activate protein kinase C.

TLS Online TPP Program

#Id: 1332

#Unit 4. Cell Communication and Cell Signaling

Gαq activate α1-Adrenergic receptor

TLS Online TPP Program

#Id: 1333

#Unit 4. Cell Communication and Cell Signaling

Cholera toxin, secreted by Vibrio cholerae Catalyze a covalent modification of the Gαs protein Inhibit GAP activity.

TLS Online TPP Program

#Id: 1334

#Unit 4. Cell Communication and Cell Signaling

The pertussis toxin, produced by Bordetella pertussis Catalyze a covalent modification of the Gαi protein preventing GDP-GTP exchange.

TLS Online TPP Program

#Id: 1335

#Unit 4. Cell Communication and Cell Signaling

The bacterial toxins that cause cholera and pertussis are enzymes that catalyze transfer of the ADP ribose moiety.