TLS Online TPP Program

#Id: 9927


HA trimers are responsible for the attachment of the virus to host cells, binding to the sialic acid. 
NA is an enzyme that cleaves N-acetyl neuraminic (sialic) acid
Within the envelope, consists of eight different strands of single- stranded RNA (ssRNA) associated with protein and RNA polymerase. 

#Unit 4. Cell Communication and Cell Signaling #Infectious Diseases #Part B Pointers
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TLS Online TPP Program

#Id: 6417

#Unit 2. Cellular Organization

The trp operon is controlled by repression and attenuation, providing a two-stage response to progressively more stringent tryptophan starvation. But attenuation alone can provide robust regulation: other amino acid operons such as leu and his rely entirely on attenuation for their control. In the case of the leucine operon, its leader peptide has four adjacent leucine codons, and the histidine operon leader peptide has seven histidine codons in a row.

TLS Online TPP Program

#Id: 6418

#Unit 2. Cellular Organization

The promoter of the araBAD operon from E. coli is activated in the presence of arabinose and the absence of glucose and directs expression of genes encoding enzymes required for arabinose metabolism. 
Unlike the cases of lac and gal genes, where a repressor and an activator work together, here two activators work together: AraC and CAP. 

TLS Online TPP Program

#Id: 6419

#Unit 2. Cellular Organization

When arabinose is present, AraC binds that sugar and adopts a configuration that allows it to bind DNA as a dimer to the adjacent half-sites, araI1 and araI2). 
Just upstream of these is a CAP site: in the absence of glucose, CAP binds here and helps activation.
In the absence of arabinose, the araBAD genes are not expressed. This is because when not bound to arabinose, AraC adopts a different conformation and binds DNA in a different way: one monomer still binds the araI1 site, but the other monomer binds a distant half-site called araO2.

TLS Online TPP Program

#Id: 6420

#Unit 2. Cellular Organization


TLS Online TPP Program

#Id: 1132

#Unit 2. Cellular Organization

Cyclin-dependent kinases are a family of Serine/Threonine kinases.

TLS Online TPP Program

#Id: 1133

#Unit 2. Cellular Organization

CDK- Cyclin in Metazoans-
G1 Phase- cyclin D–CDK4/6
G1/S Phase- cyclin E–CDK2
S Phase- cyclin A–CDK2
M Phase- cyclin A/B–CDK1